RESEARCH FOR UNDERGRADUATE STUDENTS
Undergraduate Research Assistants
Natalie Ibbetson (NHMFL-REU program, incoming - Summer 2024)
Ibukunolu B Shofolu (Fall/Winter 2023/2024)
Huyen Bui (Summer 2023)
Topic
Dynamic Nuclear Polarization
NMR spectroscopy is hampered by low sensitivity arising from the small energy gap between the nuclear Zeeman levels in a magnetic field. This often prevents NMR experiments on low gamma nuclei, low abundant isotopes, low concentration samples, or samples that are scarce or available in small amount.
A new method, called Dynamic Nuclear Polarization, holds great promise ...
HOW CAN YOU CONTRIBUTE
Spin dynamics of the electron-nuclear polarization transfer
The polarization transfer efficiency critically depends on the molecular motions that modulate the electron-nuclear hyperfine coupling. Numerical calculations can help in understanding the spin polarization mechanisms.
what Prediction of the DNP efficiency for a set of radicals and target molecules.
how Molecular dynamics and density functional theory simulations.
tech Simulation softwares; data processing methods.
EPR Spectroscopy at very high magnetic fields
Characterization of the EPR properties of organic radicals used as polarizing agents for DNP in liquids.
what Characterization of the frequency dependence and of the effect of solvent on the EPR properties of organic radicals.
how Development of protocols for sample preparation in oxigen-free atmosphere. EPR measurements at high magnetic fields and data analysis.
tech Basic wet lab methods; state-of-the-art 120-390 GHz heterodyne quasi-optical spectrometer; matlab simulations.
New polarizing agents for DNP-NMR
Polarizing agents other than nitroxide radicals have never been tested for DNP in liquid state at high magnetic fields.
what Assessment of the performance of BDPA, trityl, and galvinoxyl radicals as polarizing agents at 14.1 T.
how Quantitative DNP-NMR measurements at 14.1 T.
tech Basic wet lab methods; CW EPR at 9 GHz; DNP-NMR. instrument operating at 14.1 T.
